1 / 10
'Mr. & Mrs. Smith' - A sexy spy thriller turned into a real-life affair between Brad Pitt and Angelina Jolie, leading to the end of Pitt's marriage to Jennifer Aniston.
2 / 10
'Proof of Life' - Meg Ryan's on-screen chemistry with Russell Crowe allegedly led to the end of her marriage to Dennis Quaid.
3 / 10
'Cleopatra'- The intense romance between Elizabeth Taylor and Richard Burton on the set of this historical epic sparked a scandal and eventually led to the demise of both their marriages.
4 / 10
'Gigli' - Starring Ben Affleck and Jennifer Lopez, this notorious film not only flopped critically but also marked the beginning of the end for their highly publicized relationship.
5 / 10
'Water for Elephants' - The emotional connection between Reese Witherspoon and Robert Pattinson on set allegedly contributed to the breakdown of Witherspoon's marriage to Ryan Phillippe.
6 / 10
'Town & Country' - The troubled production and critical failure of this romantic comedy is said to have put strain on Warren Beatty and Annette Bening's marriage.
7 / 10
'Mary Shelley's Frankenstein' - This film adaptation of the classic novel reportedly played a role in the deterioration of the marriage between Kenneth Branagh and Emma Thompson, as Branagh directed the film and became romantically involved with his co-star Helena Bonham Carter.
8 / 10
'Eyes Wide Shut' - The intense and sexually charged nature of this Stanley Kubrick film reportedly led to tension in the marriage between Tom Cruise and Nicole Kidman, which eventually ended in divorce.
9 / 10
'I Know What You Did Last Summer' - The romance that blossomed between Jennifer Love Hewitt and Freddie Prinze Jr. on the set of this thriller is believed to have contributed to Prinze's breakup with his then-girlfriend.
10 / 10
'Wanderlust' - The on-screen chemistry between Jennifer Aniston and Justin Theroux in this comedy is rumored to have played a role in their subsequent relationship and marriage.