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The ABC hit show 'Grey's Anatomy' has been on the air since 2005 already. With the show in its 21st season by now, we are going to show you how the actors and actresses have changed over the course of the years...
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The role of "Meredith Grey" was a really big breakthrough for Ellen Pompeo. At the time she was already 34 years old even though her character in 'Grey's Anatomy' was roughly only 28 when she started as an intern in the surgical program at the hospital which was then still called "Seattle Grace".
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With 21 seasons in the bag, Ellen Pompeo still stars as "Meredith Grey". Pompeo signed a new contract for her role in 'Grey's Anatomy' in 2015, making her one of the 10 highest paid women in television! The show is now in its 21st season.
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Patrick Dempsey's "Dr. Derek Shepherd", whom everyone just called "McDreamy" after the first couple of episodes, started enchanting the fans of ABC's hit medical drama Grey's Anatomy when it premiered in 2005.
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Dempsey's mane is slightly more grey by now, but he's still quite an attractive man! He exited the show with the end of the eleventh season, when "McDreamy" died a heart-breaking TV death. In 2016, he appeared as "Jack Qwant" in "Bridget Jones's Baby", but mainly (as the picture suggests) he dedicates most of his spare time to race car driving and taking care of his family - he has been married to his second wife since 1999 and they have three children.
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Justin Chambers played "Alex Karev" from 2005 until 2020.
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Chambers has not changed much over the years and certainly does not look his age (53). He was an integral part of the show after "Alex" and "Meredith" became best friends, but left the show in the middle of season 17.
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Katherine Heigl played "Dr. Isobel 'Izzie' Stevens from season 1 until season 6.
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Ever since she left 'Grey's Anatomy' in 2010, Heigl has starred in a bunch of romantic comedies, like '27 Dresses', 'Life As We Know It' and 'The Ugly Truth'. From 2018 until 2019, she had a main role in the drama series 'Suits' and will star in the upcoming TV show 'Firefly Lane'. Heigl has been married to her husband, musician Josh Kelley, since 2007 and the couple have three children.
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"Dr. George O'Malley", sometimes also known as "007" or "Bambi", was also part of the original cast and he was a real fan favorite!
The ABC hit medical drama Grey's Anatomy has been on the air since 2005. We are going to show you how the actors and actresses have changed over the course of the years...
After more than a decade of air-time, we've seen actors and their respective characters come and go in Grey's. Take a look at what many of the stars are up to now in our gallery!
Enjoy!